Linn Christin Bonaventure Norbom

• Jørgensen, Kjetil Nordbø; Nerland, Stener; Slapø, Nora Berz; Norbom, Linn Bonaventure; Mørch-Johnsen, Lynn Egeland & Wortinger, Laura Anne [Show all 13 contributors for this article] (2024). Assessing regional intracortical myelination in schizophrenia spectrum and bipolar disorders using the optimized T1w/T2w-ratio. Psychological Medicine. ISSN 0033-2917. doi: 10.1017/S0033291724000503.
• Dahl, Andreas; Eilertsen, Espen Moen; Fernandez Rodriguez Cabello, Sara; Norbom, Linn B.; Tandberg, Anneli D. & Leonardsen, Esten [Show all 11 contributors for this article] (2024). Genetic and brain similarity independently predict childhood anthropometrics and neighborhood socioeconomic conditions. Developmental Cognitive Neuroscience. ISSN 1878-9293. 65, p. 1–11. doi: 10.1016/j.dcn.2023.101339. Full text in Research Archive
• Wiker, Thea; Pedersen, Mads Lund; Ferschmann, Lia; Beck, Dani; Norbom, Linn Christin Bonaventure & Dahl, Andreas [Show all 13 contributors for this article] (2023). Assessing the Longitudinal Associations Between Decision-Making Processes and Attention Problems in Early Adolescence. Research on Child and Adolescent Psychopathology. ISSN 2730-7166. doi: 10.1007/s10802-023-01148-8. Full text in Research Archive
• Wiker, Thea; Norbom, Linn B.; Beck, Dani; Agartz, Ingrid; Andreassen, Ole A. & Alnæs, Dag [Show all 14 contributors for this article] (2023). Reaction Time Variability in Children Is Specifically Associated With Attention Problems and Regional White Matter Microstructure. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. ISSN 2451-9022. 8(8), p. 832–840. doi: 10.1016/j.bpsc.2023.03.010. Full text in Research Archive
• Beck, Dani; Ferschmann, Lia; MacSweeney, Niamh; Norbom, Linn Christin Bonaventure; Wiker, Thea & Aksnes, Eira Ranheim [Show all 15 contributors for this article] (2023). Puberty differentially predicts brain maturation in male and female youth: A longitudinal ABCD Study. Developmental Cognitive Neuroscience. ISSN 1878-9293. 61. doi: 10.1016/j.dcn.2023.101261. Full text in Research Archive
• Kjelkenes, Rikka; Wolfers, Thomas; Alnæs, Dag; Norbom, Linn Christin Bonaventure; Voldsbekk, Irene & Holm, Madelene Christin [Show all 11 contributors for this article] (2022). Deviations from normative brain white and gray matter structure are associated with psychopathology in youth. Developmental Cognitive Neuroscience. ISSN 1878-9293. 58. doi: 10.1016/j.dcn.2022.101173. Full text in Research Archive
• Fernandez-Cabello, Sara; Alnæs, Dag; van der Meer, Dennis; Dahl, Andreas; Holm, Madelene Christin & Kjelkenes, Rikka [Show all 12 contributors for this article] (2022). Associations between brain imaging and polygenic scores of mental health and educational attainment in children aged 9–11. NeuroImage. ISSN 1053-8119. 263. doi: 10.1016/j.neuroimage.2022.119611. Full text in Research Archive
• Norbom, Linn Christin Bonaventure; Hanson, Jamie; van der Meer, Dennis; Ferschmann, Lia; Røysamb, Espen & von Soest, Tilmann [Show all 10 contributors for this article] (2022). Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents. Developmental Cognitive Neuroscience. ISSN 1878-9293. 56. doi: 10.1016/j.dcn.2022.101132. Full text in Research Archive
• Norbom, Linn Christin Bonaventure; Ferschmann, Lia; Parker, Nadine; Agartz, Ingrid; Andreassen, Ole Andreas & Paus, Tomas [Show all 8 contributors for this article] (2021). New insights into the dynamic development of the cerebral cortex in childhood and adolescence: Integrating macro- and microstructural MRI findings. Progress in Neurobiology. ISSN 0301-0082. 204, p. 1–19. doi: 10.1016/j.pneurobio.2021.102109. Full text in Research Archive
• Rokicki, Jaroslav; Wolfers, Thomas; Nordhøy, Wibeke; Tesli, Natalia; Quintana, Daniel & Alnæs, Dag [Show all 20 contributors for this article] (2020). Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders. Human Brain Mapping. ISSN 1065-9471. 42(6), p. 1714–1726. doi: 10.1002/hbm.25323. Full text in Research Archive
• Bang, Lasse; Tamnes, Christian Krog; Norbom, Linn Christin Bonaventure; Thomassen, Rut Anne; Solberg, Jill & SKOTTE, LAILA HOLGERSEN [Show all 9 contributors for this article] (2020). Associations of age, body mass index and biochemical parameters with brain morphology in patients with anorexia nervosa. European Eating Disorders Review. ISSN 1072-4133. 29(1), p. 74–85. doi: 10.1002/erv.2803. Full text in Research Archive
• Norbom, Linn Christin Bonaventure; Rokicki, Jaroslav; van der Meer, Dennis; Alnæs, Dag; Doan, Nhat Trung & Moberget, Torgeir [Show all 10 contributors for this article] (2020). Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents. Translational Psychiatry. ISSN 2158-3188. 10(251). doi: 10.1038/s41398-020-00931-1. Full text in Research Archive
• Norbom, Linn Christin Bonaventure; Rokicki, Jaroslav; Alnæs, Dag; Kaufmann, Tobias; Doan, Nhat Trung & Andreassen, Ole Andreas [Show all 8 contributors for this article] (2020). Maturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study. Human Brain Mapping. ISSN 1065-9471. 41(16), p. 4676–4690. doi: 10.1002/hbm.25149. Full text in Research Archive
• Moberget, Torgeir; Alnæs, Dag; Kaufmann, Tobias; Doan, Nhat Trung; Còrdova Palomera, Aldo & Norbom, Linn Christin Bonaventure [Show all 10 contributors for this article] (2019). Cerebellar Gray Matter Volume Is Associated With Cognitive Function and Psychopathology in Adolescence. Biological Psychiatry. ISSN 0006-3223. 86(1), p. 65–75. doi: 10.1016/j.biopsych.2019.01.019. Full text in Research Archive
• Elvsåshagen, Torbjørn; Mutsaerts, Henri J.M.M; Zak, Nathalia; Norbom, Linn Christin Bonaventure; Quiraishi, Sophia & Pedersen, Per Øystein Heiberg [Show all 11 contributors for this article] (2018). Cerebral blood flow changes after a day of wake, sleep, and sleep deprivation. NeuroImage. ISSN 1053-8119. 186, p. 497–509. doi: 10.1016/j.neuroimage.2018.11.032. Show summary

  Elucidating the neurobiological effects of sleep and wake is an important goal of the neurosciences. Whether and how human cerebral blood flow (CBF) changes during the sleep-wake cycle remain to be clarified. Based on the synaptic homeostasis hypothesis of sleep and wake, we hypothesized that a day of wake and a night of sleep deprivation would be associated with gray matter resting CBF (rCBF) increases and that sleep would be associated with rCBF decreases. Thirty-eight healthy adult males (age 22.1 ± 2.5 years) underwent arterial spin labeling perfusion magnetic resonance imaging at three time points: in the morning after a regular night's sleep, the evening of the same day, and the next morning, either after total sleep deprivation (n = 19) or a night of sleep (n = 19). All analyses were adjusted for hematocrit and head motion. rCBF increased from morning to evening and decreased after a night of sleep. These effects were most prominent in bilateral hippocampus, amygdala, thalamus, and in the occipital and sensorimotor cortices. Group × time interaction analyses for evening versus next morning revealed significant interaction in bilateral lateral and medial occipital cortices and in bilateral insula, driven by rCBF increases in the sleep deprived individuals and decreases in the sleepers, respectively. Furthermore, group × time interaction analyses for first morning versus next morning showed significant effects in medial and lateral occipital cortices, in anterior cingulate gyrus, and in the insula, in both hemispheres. These effects were mainly driven by CBF increases from TP1 to TP3 in the sleep deprived individuals. There were no associations between the rCBF changes and sleep characteristics, vigilant attention, or subjective sleepiness that remained significant after adjustments for multiple analyses. Altogether, these results encourage future studies to clarify mechanisms underlying sleep-related rCBF changes.

• Norbom, Linn Christin Bonaventure; Doan, Nhat Trung; Alnæs, Dag; Kaufmann, Tobias; Moberget, Torgeir & Rokicki, Jaroslav [Show all 9 contributors for this article] (2018). Probing brain developmental patterns of myelination and associations with psychopathology in youths using gray/white matter contrast. Biological Psychiatry. ISSN 0006-3223. doi: 10.1016/j.biopsych.2018.09.027. Full text in Research Archive
• van der Meer, Dennis; Rokicki, Jaroslav; Kaufmann, Tobias; Còrdova Palomera, Aldo; Moberget, Torgeir & Alnæs, Dag [Show all 54 contributors for this article] (2018). Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Molecular Psychiatry. ISSN 1359-4184. p. 1–13. doi: 10.1038/s41380-018-0262-7. Full text in Research Archive
• Berg, Akiah Ottesen; Jørgensen, Kjetil Nordbø; Nerhus, Mari; Athanasiu, Lavinia; Popejoy, Alice & Bettella, Francesco [Show all 13 contributors for this article] (2018). Vitamin D levels, brain volume, and genetic architecture in patients with psychosis. PLOS ONE. ISSN 1932-6203. 13(8). doi: 10.1371/journal.pone.0200250. Full text in Research Archive
• Elvsåshagen, Torbjørn; Zak, Nathalia; Norbom, Linn Christin Bonaventure; Pedersen, Per Øystein Heiberg; Quraishi, Sophia H. & Bjørnerud, Atle [Show all 11 contributors for this article] (2017). Evidence for cortical structural plasticity in humans after a day of waking and sleep deprivation. NeuroImage. ISSN 1053-8119. 156, p. 214–223. doi: 10.1016/j.neuroimage.2017.05.027. Full text in Research Archive
• Quintana, Daniel; Elvsåshagen, Torbjørn; Zak, Nathalia; Norbom, Linn Christin Bonaventure; Pedersen, Per Øystein Heiberg & Quraishi, Sophia H. [Show all 12 contributors for this article] (2017). Diurnal Variation and twenty-four hour sleep deprivation do not alter supine heart rate variability in healthy male young adults. PLOS ONE. ISSN 1932-6203. 12:e0170921(2), p. 1–16. doi: 10.1371/journal.pone.0170921. Full text in Research Archive
• Jørgensen, Kjetil Nordbø; Nerland, Stener; Norbom, Linn Christin Bonaventure; Doan, Nhat Trung; Nesvåg, Ragnar & Mørch-Johnsen, Lynn [Show all 11 contributors for this article] (2016). Increased MRI-based cortical grey/white-matter contrast in sensory and motor regions in schizophrenia and bipolar disorder. Psychological Medicine. ISSN 0033-2917. 46(9), p. 1971–1985. doi: 10.1017/S0033291716000593.
• Kaufmann, Tobias; Elvsåshagen, Torbjørn; Alnæs, Dag; Zak, Nathalia; Pedersen, Per Øystein Heiberg & Norbom, Linn Christin Bonaventure [Show all 17 contributors for this article] (2015). The brain functional connectome is robustly altered by lack of sleep. NeuroImage. ISSN 1053-8119. 127, p. 324–332. doi: 10.1016/j.neuroimage.2015.12.028. Show summary

  Sleep is a universal phenomenon necessary for maintaining homeostasis and function across a range of organs. Lack of sleep has severe health-related consequences affecting whole-body functioning, yet no other organ is as severely affected as the brain. The neurophysiological mechanisms underlying these deficits are poorly understood. Here, we characterize the dynamic changes in brain connectivity profiles inflicted by sleep deprivation and how they deviate from regular daily variability. To this end, we obtained functional magnetic resonance imaging data from 60 young, adult male participants, scanned in the morning and evening of the same day and again the following morning. 41 participants underwent total sleep deprivation before the third scan, whereas the remainder had another night of regular sleep. Sleep deprivation strongly altered the connectivity of several resting-state networks, including dorsal attention, default mode, and hippocampal networks. Multivariate classification based on connectivity profiles predicted deprivation state with high accuracy, corroborating the robustness of the findings on an individual level. Finally, correlation analysis suggested that morning-to-evening connectivity changes were reverted by sleep (control group)-a pattern which did not occur after deprivation. We conclude that both, a day of waking and a night of sleep deprivation dynamically alter the brain functional connectome.

• Elvsåshagen, Torbjørn; Norbom, Linn Christin Bonaventure; Pedersen, Per Øystein Heiberg; Quraishi, Sophia H.; Bjørnerud, Atle & Malt, Ulrik Fredrik [Show all 8 contributors for this article] (2015). Widespread changes in white matter microstructure after a day of waking and sleep deprivation. PLOS ONE. ISSN 1932-6203. 10:e0127351(5). doi: 10.1371/journal.pone.0127351. Full text in Research Archive

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• Norbom, Linn Christin Bonaventure; Hanson, Jamie; van der Meer, Dennis; Ferschmann, Lia; Røysamb, Espen & von Soest, Tilmann [Show all 10 contributors for this article] (2023). Erratum to “Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents” [Dev. Cogn. Neurosci. 56C (2022) 101132] (Developmental Cognitive Neuroscience (2022) 56, (S1878929322000755), (10.1016/j.dcn.2022.101132)). Developmental Cognitive Neuroscience. ISSN 1878-9293. 61. doi: 10.1016/j.dcn.2023.101225.
• Jørgensen, Kjetil Nordbø; Nerland, Stener; Norbom, Linn Christin Bonaventure; Doan, Nhat Trung; Nesvåg, Ragnar & Haukvik, Unn Kristin H. [Show all 10 contributors for this article] (2015). Increased cortical gray/white matter intensity contrast in schizophrenia and bipolar disorder compared to healthy controls.

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